Is bone tuberculosis dangerous

Forecast & course

Tuberculosis used to be one of the most terrible epidemics ("white plague"). Many people were carried away by them in the truest sense of the word ("consumption"). Above all through hygiene measures and better nutrition, tuberculosis has decreased dramatically. Another significant decrease was achieved by drugs that act against tuberculosis. However, the effects of globalization and the resulting migration movements with immigration of people from countries with a high incidence of tuberculosis can also be felt in industrialized nations such as Germany. For example, tuberculosis among repatriates or immigrants from the states of the former Soviet Union or other regions of the world with high tuberculosis rates is significantly higher than among the population born in Germany. Also the increase in resistance
Bacteria can develop resistance to certain drugs - that is, they become insensitive to these drugs. The drugs, especially antibiotics, are no longer effective against these bacteria.
Resistant pathogens develop - especially with large amounts of pathogen - either through spontaneous gene changes (mutations) or through selective reproduction (selection) of naturally occurring resistant bacterial subpopulations, e.g. due to inadequate or prematurely discontinued therapy.
Tuberculosis strains - and here too the states of the former Soviet Union are particularly affected - is reflected in the epidemiological development in Germany.

Uncomplicated tuberculosis can be cured with sufficiently long and appropriate drug treatment, and the risk of a relapse is then extremely low. The sooner the diagnosis is made and the therapy is started, the better the chances of recovery. Serious comorbidities, such as those that often occur in older patients, pose a particular challenge for the attending physician. Therefore, care should be provided by physicians with sufficient experience in tuberculosis therapy, especially if drug intolerance and / or resistance make deviations from the standardized treatment necessary (see also "Therapy"). If the standard medication cannot be used, the treatment is extended, sometimes for a period of up to two years. Patients with pathogens that show complicated resistance patterns - in the worst case with ineffectiveness against any of the five standard drugs - are very difficult to treat and their therapy has significantly poorer prospects of success.