What types of fumigation processes are there

Bottled? Why, surely. And fast.

After production, many pharmaceuticals are filled into small bottles, so-called vails. A shortening of the filling time can accelerate the time-to-market and increase productivity. In order to prevent time-consuming disruptive factors such as splashing, overflowing and foaming, virtual experiments can be carried out with simulations and in this way a wide variety of concepts, designs and conditions can be tested. With this basic knowledge, the filling process can be optimally designed for fast throughput. In addition, optimized flow conditions ensure high product quality during filling.

Air upward? High time for process optimization

Manufacturers of filling and closing machines must optimally adapt their systems to the respective individual needs and specific requirements of their customers. Of course, filling and sealing requires sterile conditions and a high degree of safety and reliability. Since liquid pharmaceuticals often react sensitively to oxygen, freshly filled vails or ampoules are gassed several times with nitrogen before they are closed in order to displace the remaining air from the container. fluiosystem helps to analyze this fumigation process, to show the behavior of nitrogen and air concentrations and to work out an optimal solution from this knowledge that keeps the residual oxygen content in the bottle as low as possible. And that quickly and reliably.

Optimal filling brought under lock and key

Taking into account the immediate surroundings (possibly laminar flow conditions), we analyze in detail what actually happens in the Vail and the surrounding area during the fumigation process. From this we derived design variants through which the nitrogen stream flows into the bottle in a much more targeted manner and can efficiently displace the oxygen there. The proposed optimizations, such as the adjustment of the nozzle parameters or the volume flow, can be checked virtually again before the actual implementation in the system in order to ensure an optimal result in advance. With this in mind, we support you in completing projects in the most fulfilling way.

Is everything in flux? From mixing to separating: pharmaceutical processes in perfection

Minimal changes to the flow conditions often result in considerable improvements in the entire process flow and in product quality - and this in many different processes and manufacturing areas in the chemical and pharmaceutical industries. Regardless of whether it is about mixing, separating, drying, liquid transport or heat generation: The process reliability and product quality as well as the energy efficiency of systems depend to a large extent on the currents inside the system. And it pays off in more ways than one to take these into account in the system and process planning right from the start. HTCO has decades of experience and an optimally coordinated service portfolio in order to allow valuable knowledge to flow into the planning in advance and thus contribute to considerable cost savings.