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Dexamphetamine

Dexamphetamine (Trade name in Germany: Assassin) is an active ingredient from the group of amphetamines that can be used to treat ADHD in children and adolescents. For the treatment of adult ADHD, dexamphetamine can only be considered as an off-label prescription due to the lack of approval. In Germany, dexamphetamine is currently only available in tablet form in doses of 5, 10 and 20 mg.

2011 saw the introduction of Assassin A finished product containing dexamphetamine was approved for the first time in Germany.[1] The preparation is made available by the German pharmaceutical distributor MEDICE Arzneimittel PĆ¼tter.

If dexamphetmin is misused, there is a risk of addiction.[2][3]

indication

Dexamphetamine has been approved for the treatment of children 6 years and older and adolescents with ADHD since 2011. The administration of Attentin is indicated if previous attempts at treatment with atomoxetine or methylphenidate have not produced the desired or no improvements.

Furthermore, dexamphetamine can be prescribed off label for the treatment of therapy-resistant depression.

Side effects

Side effects without specifying the frequency

Heart disease, heart attack, palpitations, palpitations, increased blood pressure, dilated pupils, visual disturbances, abdominal cramps, bowel inflammation due to circulatory disorder, diarrhea, dry mouth, nausea, chest pain, death from cardiovascular collapse, slowed growth and swelling, hypersensitivity reactions (including hypersensitivity) Shock), sudden deaths, acidification of the body, refusal to eat, weight loss, muscle tissue breakdown (rhabdomyolysis), unsteady gait, untargeted movements of the arms and face, difficulty concentrating, cramps, drowsiness, twitching of the muscles in the face, taste disturbance, fatigue, headache, overactivity, exaggerated reflexes, brains neuroleptic syndrome, stroke, tremors, Tourette's syndrome, aggressive behavior, fear, confusion, delirium, depression, drug addiction, moodiness, weakness of feeling, excessive exaggeration, delusions, impairment Performance changes in brain performance tests, insomnia, irritability, altered libido, nervousness, night anxiety, obsessive-compulsive behavior, panic states, paranoia, psychosis (or similar reactions), restlessness, nervous twitching (tics), kidney damage, impotence, hair loss, rash, sweating, hives .[4]

Rare side effects

Decrease in blood pressure, cardiovascular breakdown, inflammation of blood vessels in the brain.

Isolated side effects

In the case of poisoning, transient hyperactivity occurred, along with body overheating, hyperacidity and death from cardiovascular breakdown.

Application restrictions

Dexamphetamine must not be used in children under 6 years of age or in adults, as its safety and effectiveness have not yet been established in this age group. A prescription to adults with the costs being covered by the health insurances is currently only possible via off-label prescriptions.

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See also

Web links

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