American scientists have found that sudden loss of pressure when changing body position (also known as orthostatic collapse) in the elderly is associated with increased risk of dementia. To do this, they analyzed data on more than two thousand older people over the 12 years of the study, participants with systolic orthostatic collapse, dementia was diagnosed in 37 percent more often — and taking into account all other factors. Article published in the journal Neurology.
Orthostatic collapse — dizziness when changing position caused due to a sharp decline in blood pressure when a person stands up or sits up sharply, the blood does not have time to go to the brain, which well-being can rapidly deteriorate (beyond blackouts and dizziness can even occur fainting). The cause of the disturbed vascular tone: it is more common in adolescents and older people, and if at first it is usually not dangerous and goes with age, for people older orthostatic collapse — a risk factor for cardiovascular disease and premature death.
Lori roach (Laure Rouch) from the University of California in San Francisco suggested that orthostatic collapse can also be a risk factor for other age-related diseases — dementia. To do this, they collected data on 2131 volunteer at the age of 73 years: at the beginning of the study none of them dementia was not. The presence of orthostatic collapse — a reduction in either systolic pressure by 15 mm Hg, or diastolic blood pressure by 7 millimeters of mercury after a sharp rise from a seated position — scientists are evaluated during inspections for five years. If a sharp decline in pressure was observed in the participant during at least one-third of all examinations, the researchers concluded that orthostatic collapse it happens, and all such participants have been 15 percent.
Over the next 12 years of observations of dementia were diagnosed in 21.7% of participants. Among the participants, which happened often systolic orthostatic collapse, the risk of dementia was 40 percent higher. Considering all other possible factors in the development of the disease (Smoking, diabetes, excess weight, alcohol consumption, and also a variant of the gene APOE, which is associated with an increased risk of dementia), the chance that participants with systolic orthostatic collapse will be diagnosed with dementia, was 37 percent.
The authors concluded that orthostatic collapse in old age (and in General, sudden changes in pressure) can be a marker for increased risk of dementia. Moreover, they note that their study is the observation, though, and say that the control pressure must be in the prevention of dementia.
And the risk of dementia affect experienced traumatic brain injury — and to let you know they may in 30 years.