The study, which gathered data from 25 European countries showed that the majority of children, including infants, COVID-19 proceeds in the form of light. While 8 percent of pediatric patients develop severe disease requiring intensive care and respiratory support. The work, published in the journal The Lancet Child & Adolescent Health, presented data on the efficacy of the used to treat COVID-19 drugs. However, they were uninformative, as the number of children receiving such treatment, was small.
While the current COVID-19 children dedicated not so much research. Most of the works on this account take into account only the data for China, and they are descriptions of clinical cases or epidemiological reports containing information on the number of patients without any interpretation. Studies in Spain and Italy was conducted on a small sample of children with confirmed COVID-19 and was a short message from the preliminary findings.
Researchers from England, Austria, Spain and other European countries under the leadership of Mark Tebrugge (Marc Tebruegge) from University College London conducted an analysis of 582 cases COVID-19 in children 82 health institutions from 25 countries of Europe. For coordination of data collection used the resources of the European study group of the pediatric tuberculosis network (ptbnet), which included experts in infectious diseases in children and pediatric pulmonologists. Members of this group was to transmit standardized data on cases COVID-19 in children, which they were treated, and all identified child cases in the institution where they work. Information collected from 1 to 24 April 2020 — in the midst of the epidemic in Europe.
The average age of children was 5 years (interquartile range 0.5-12 years), 29 percent were infants. The source of infection in 56 percent of cases were one of the parents of the child for 4 percent of the patients brothers and sisters. For the remaining 40 per cent failed to detect contacts with patients.
Hospitalization needed 363 of the child (62 percent), the state of the remaining 219 children allowing them to be treated at home. Approximately 13 percent of the required oxygen support. 31 (5%) patient was on CPAP-therapy (constant positive pressure), and 25 (4%) children required mechanical ventilation (including 14 patients who initially were treated with CPAP). One patient was treated with extracorporeal membrane oxygenation. The average duration of artificial ventilation was 7 days (interquartile range 2-11 days). At multivariate analysis revealed that male sex (p = 0.033) under 1 month (p = 0,0035) with signs of infections of the lower respiratory tract early in the disease (p < 0.0001) more frequently needed respiratory support.