The Ministry of defence and the national research centre of epidemiology and Microbiology named Gamalei received permission to start phase one clinical trials of a vaccine against coronavirus SARS-CoV-2. The tests will involve 86 soldiers and civilian volunteers, they are now on a two-week quarantine. The resolution and brief description of research available on the website of the Ministry of health.
A vaccine against the coronavirus SARS-CoV-2 was developed by the Ministry of defence in cooperation with the National research centre of epidemiology and Microbiology named Gamalei, the drug has successfully passed preclinical trials on animals. In addition, unofficially, the vaccine was tested by the staff of the center of Gamaliel (Association of clinical research called this a gross violation of the norms of clinical trials). On 16 June, the Ministry of health of has allowed to hold their first formal clinical trials of the drug.
For the first and second phases of clinical trials took 86 volunteers from the civilian and the military, now they are on a two-week isolation (half in the Main military clinical Burdenko hospital and the other half in Sechenovskiy medical University). Every day all participants take tests for antibodies and viral RNA.
After the quarantine, half of the volunteers will intramuscularly administered vaccine solution Gam-KOVID VAK, and the rest — reconstituted lyophilisate (dried drug) Gam-KOVID VAK Leo. In the first phase of tests will investigate safety, tolerability and immunogenicity (production of antibodies) vaccine. To monitor the health status and immunity of volunteers plan until December 31, 2020.
In the U.S. clinical trials of a vaccine against SARS-CoV-2 began in March. Then in the material to”Catch and prevent” we dealt with the development of vaccines, how much time take their tests and if they can stop the pandemic.